Kyle M. Lancaster

Professor

Publications

Bioinorganic Chemistry of the Nitrogen Cycle

Bollmeyer, M. M.; Coleman, R. E.; Majer, S. H.; Ferrao, S. D.; Lancaster, K. M. Cytochrome P460 Cofactor Maturation Proceeds via Peroxide- Dependent Post-Translational Modification, J. Am. Chem. Soc. 2023, 145, 14404–14416.
Coleman, R.E.; Vilbert, A.C.; Lancaster, K.M. The Heme–Lys Cross-Link in Cytochrome P460 Promotes Catalysis by Enforcing Secondary Coordination Sphere Architecture, Biochemistry 2020, 59, 2289-2298.
Ferousi, C.; Majer, S.H.; DiMucci, I.M.; Lancaster, K.M. Biological and Bioinspired Inorganic N–N Bond-Forming Reactions, Chem. Rev. 2020, 120, 5252-5307.
Smith, M.A.; Majer, S.H.; Vilbert, A.C.; Lancaster, K.M. Controlling a burn: outer-sphere gating of hydroxylamine oxidation by a distal base in cytochrome P460, Chem. Sci. 2019, 10, 3756-3764.
Lancaster, K.M.; Caranto, J.D.; Majer, S.H.; Smith, M.A. Alternative Bioenergy: Updates to and Challenges in Nitrification Metalloenzymology, Joule 2018, 2, 421–441.
Vilbert, A.C.; Caranto, J.D; Lancaster, K.M. Influences of the Heme-lysine Crosslink in Cytochrome P460 over Redox Catalysis and Nitric Oxide Sensitivity, Chem. Sci. 2018, 9, 368–379.
Caranto, J.D.; Lancaster, K.M. Nitric Oxide is an Obligate Bacterial Nitrification Intermediate Produced by Hydroxylamine Oxidoreductase. Proc. Natl. Acad. Sci. U.S.A. 2017, 31, 8217–8222.
Caranto, J. D.; Vilbert, A. C.; Lancaster, K. M. Nitrosomonas europaea Cytochrome P460 Is a Direct Link between Nitrification and Nitrous Oxide Emission. Proc. Natl. Acad. Sci. USA, 2016, 113, 14704–14709.

Transition Metal Electronic Structure/X-ray Spectroscopy

DiMucci, I. M.; Titus, C. J.; Nordlund, D. N.; Bour, J. R.; Chong, E.; Grigas, D. P.; Hu, C.-H.; Kosobokov, M. D.; Martin, C. D.; Mirica, L. M.; Nebra, N. ; Vicic, D. A.; Yorks, L. L.; Yruegas, S.; MacMillan, S. N.; Shearer, J.; Lancaster, K. M. Scrutinizing Formally Ni^IV Centers through the Lenses of Core Spectroscopy, Molecular Orbital Theory, and Valence Bond Theory. Chem. Sci. 2023, 14, 6915–6929.
DiMucci, I.M.; Lukens, J.T.; Chatterjee, S.; Carsch, K.M.; Titus, C.J.; Lee, S.J.; Nordlund, D.; Betley, T.A.; MacMillan, S.N.; Lancaster, K.M. The Myth of d⁸ Copper(III), J. Am. Chem. Soc. 2019, 141, 18508-18520.
Carsch, K.M.; DiMucci, I.M.; Iovan, D.A.; Li, A.; Zheng, S.; Titus, C.J.; Lee, S.J.; Irwin, K.D.; Nordlund, D.; Lancaster, K.M.; Betley, T.A., Synthesis of a copper-supported triplet nitrene complex pertinent to copper-catalyzed amination, Science 2019, 365, 1138-1143.
Lukens, J.T.; DiMucci, I.M.; Kurogi, T.; Mindiola, D.J.; Lancaster, K.M., Scrutinizing metal–ligand covalency and redox non-innocence via nitrogen K-edge X-ray absorption spectroscopy, Chem. Sci. 2019, 10, 5044–5055.
MacMillan, S. N.; Lancaster, K. M. X-ray Spectroscopic Interrogation of Transition Metal-Mediated Homogeneous Catalysis: Primer and Case Studies. ACS Catalysis, 2017, 7, 1776–1791.
Walroth, R. C.; Lukens, J. T.; MacMillan, S. N.; Finkelstein, K. D.; Lancaster, K. M. Spectroscopic Evidence for a 3d¹⁰ Ground State Electronic Configuration and Ligand Field Inversion in [Cu(CF₃)₄]^1– J. Am. Chem. Soc. 2016, 138, 1922–1931.

678A ST Olin
kml236@cornell.edu
607/255-0502

Education

Postdoc, Cornell University
PhD Chemistry, California Institute of Technology
BA Molecular Biology, Pomona College

Departments and programs

Keywords

inorganic chemistry, bioinorganic chemistry, synthesis, outer-sphere coordination, small-molecule activation, climate change, nitrogen cycle

Peng Chen

Peter J. W. Debye Professor

Publications

See complete publication list at Group Website.

U. Chakraborty,^† Y. Park,^† K. Sengupta, W. Jung, C. Joshi, D. Francis, P. Chen* "A ‘through-DNA’ mechanism for co-regulation of metal uptake and efflux" Nature Commun. 2024, 15, 10555.
W. Jung,* T.-Y. Chen, A. G. Santiago, P. Chen* "Memory effects of transcription regulator-DNA interactions in bacteria" Proc. Natl. Acad. Sci. U.S.A. 2024, 121, e2407647121.
M. Zhao, W. Li, M. Yang, Z. Zhao, R. Ye, X. Mao, P. Padgett, P. Chen* "Long-range enhancement of micropollutant adsorption on metal-promoted photocatalysts" Nature Catal. 2024, 7, 912-920.
L. Xu,^† R. Ye,^† M. Mavrikakis,* P. Chen* "Molecular-scale insights into cooperativity switching of xTAB adsorption on gold nanoparticles" ACS Cent. Sci. 2024, 10, 65-76.
R. Ye,^† X. Sun,^† X. Mao,^† F. Alfonso, S. Baral, C. Liu, G. Coates, P. Chen* "Optical sequencing of single synthetic polymers" Nature Chem. 2024, 16, 210-217.
B. Fu,^† X. Mao,^† Y. Park, Z. Zhao, T. Yan, W. Jung, D. H. Francis, W. Li, B. Pian, F. Salimijazi, M. Suri, T. Hanrath, B. Barstow, P. Chen* "Single-cell multimodal imaging uncovers energy conversion pathways in biohybrids" Nature Chem. 2023, 15, 1400-1407.
S. Baral,^† C. Liu,^†,* X. Mao, G. W. Coates, P. Chen* "Tuning single polymer growth via hydrogen bonding in conformational entanglements" ACS Cent. Sci. 2022, 8, 1116-1124.
X. Mao, P. Chen* "Inter-facet junction effects on particulate photoelectrodes" Nature Mater. 2022, 21, 331-337.
R. Ye,^† M. Zhao,^† X. Mao, Z. Wang, D. A. Garzón, H. Pu, Z. Zhao, P. Chen* "Nanoscale cooperative adsorption for materials control" Nature Commun. 2021, 12, 4287.
S. Baral, C. Liu, U. K. Chakraborty, K. Kubo, X. Mao, G. W. Coates, P. Chen* "Single-chain polymerization dynamics and conformational mechanics of conjugated polymers" Chem 2021, 7, 2175-2189.
B. Fu,^† K. Sengupta,^† L. A. Genova,^† A. G. Santiago, W. Jung, L. Krzeminski, U. K. Chakraborty, W. Zhang, P. Chen* "Metal-induced sensor mobilization turns on affinity to activate regulator for metal detoxification in live bacteria" Proc. Natl. Acad. Sci. U.S.A. 2020, 117, 13248-13255.
L. A. Genova,^† M. F. Roberts,^† Y.-C. Wong, C. E. Harper, A. G. Santiago, B. Fu, A. Srivastava, W. Jung, L. M. Wang, L. Krzeminski, X. Mao, X. Sun, C.-Y. Hui, P. Chen,* C. J. Hernandez* "Mechanical stress compromises multicomponent efflux complexes in bacteria" Proc. Natl. Acad. Sci. U.S.A. 2019, 116, 25462-25467.
X. Mao, C. Liu, M. Hesari, N. Zou, P. Chen* "Super-resolution imaging of nonfluorescent reactions via competition" Nature Chem. 2019, 11, 687-694.
C. Liu,^† K. Kubo,^† E. Wang,^† K.-S. Han, F. Yang, G. Chen, F. A. Escobedo,* G. W. Coates,* P. Chen* "Single polymer growth dynamics" Science 2017, 358, 353-355.
J. B. Sambur, T.-Y. Chen, E. Choudhary, G. Chen, E. J. Nissen, E. M. Thomas, N. Zou, P. Chen* "Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes" Nature 2016, 530, 77-80.

782A ST Olin
pc252@cornell.edu
607/254-8533

Education

Postdoc, Harvard University, 2004-2005
PhD, Stanford University, 2004
BS, Nanjing University, 1997

Departments and programs

Keywords

Single-molecule super-resolution imaging & manipulation, nanoscale (photo)(electro)catalysis, polymerization catalysis, bioinorganic/biophysical chemistry, bacterial cell imaging, solar and biological energy conversion

Nozomi Ando

Associate Professor

Publications

Education

Departments and programs

Links

Kyle M. Lancaster

Professor

Publications

Education

Departments and programs

Links

Keywords

Brian Crane

George W. and Grace L. Todd Professor

Publications

Education

Departments and programs

Links

Keywords

Peng Chen

Peter J. W. Debye Professor

Publications

Education

Departments and programs

Links

Keywords