Nozomi Ando
Associate Professor
Education
• Postdoc, Chemistry, Massachusetts Institute of Technology
• PhD, Physics, Cornell University
• BS, Physics, Massachusetts Institute of Technology
Justin J. Wilson
Associate Professor
Publications
- Aohan Hu and Justin J. Wilson. “Advancing Chelation Strategies for Large Metal Ions for Nuclear Medicine Applications.” Acc. Chem. Res. 2022, 55, 904–915.
- Chilaluck C. Konkankit, Sierra C. Marker, Nicholas P. Bigham, Darren S. Dale, David B. Zax, Daniel R. Lorey II, and Justin J. Wilson. “Development and Implementation of Nuclear Chemistry Experiments at the Undergraduate Level.” J. Chem. Educ. 2021, 98, 3831–3840.
- Aohan Hu, Eduardo Aluicio-Sarduy, Victoria Brown, Samantha N. MacMillan, Kaelyn V. Becker, Todd E. Barnhart, Valery Radchenko, Caterina F. Ramogida, Jonathan W. Engle, and Justin J. Wilson. “Py-Macrodipa: A Janus Chelator Capable of Binding Medicinally Relevant Rare-Earth Radiometals of Disparate Sizes.” J. Am. Chem. Soc. 2021, 143, 10429–10440.
- Joshua J. Woods and Justin J. Wilson. “A Dinuclear Persulfide‐Bridged Ruthenium Compound is a Hypoxia‐Selective Hydrogen Sulfide (H2S) Donor.” Angew. Chem. Int. Ed. 2021, 60, 1588–1592.
- Sierra C. Marker, A. Paden King, Robert V. Swanda, Brett Vaughn, Eszter Boros, Shu-Bing Qian, and Justin J. Wilson. “Exploring Ovarian Cancer Cell Resistance to Rhenium Anticancer Complexes.” Angew. Chem. Int. Ed. 2020, 59, 13391–13400.
Education
- Seaborg Institute Postdoctoral Fellow, Los Alamos National Laboratory
- PhD, Massachusetts Institute of Technology
- BS, University of California, Berkeley
Departments and programs
Links
Keywords
medicinal inorganic chemistry, radiopharmaceuticals, inorganic synthesis, ligand design
Kyle M. Lancaster
Professor
Publications
Bioinorganic Chemistry of the Nitrogen Cycle
- Rathnayaka, S.C.; Islam, S.M.; DiMucci, I.M.; MacMillan, S.N.; Lancaster, K.M.; Mankad, N.P. Probing the electronic and mechanistic roles of the μ4-sulfur atom in a synthetic CuZ model system, Chem. Sci. 2020, 11, 3441-3447.
- Coleman, R.E.; Vilbert, A.C.; Lancaster, K.M. The Heme–Lys Cross-Link in Cytochrome P460 Promotes Catalysis by Enforcing Secondary Coordination Sphere Architecture, Biochemistry 2020, 59, 2289-2298.
- Ferousi, C.; Majer, S.H.; DiMucci, I.M.; Lancaster, K.M. Biological and Bioinspired Inorganic N–N Bond-Forming Reactions, Chem. Rev. 2020, 120, 5252-5307.
- Smith, M.A.; Majer, S.H.; Vilbert, A.C.; Lancaster, K.M. Controlling a burn: outer-sphere gating of hydroxylamine oxidation by a distal base in cytochrome P460, Chem. Sci. 2019, 10, 3756-3764.
- Lancaster, K.M.; Caranto, J.D.; Majer, S.H.; Smith, M.A. Alternative Bioenergy: Updates to and Challenges in Nitrification Metalloenzymology, Joule 2018, 2, 421–441.
- Vilbert, A.C.; Caranto, J.D; Lancaster, K.M. Influences of the Heme-lysine Crosslink in Cytochrome P460 over Redox Catalysis and Nitric Oxide Sensitivity, Chem. Sci. 2018, 9, 368–379.
- Caranto, J.D.; Lancaster, K.M. Nitric Oxide is an Obligate Bacterial Nitrification Intermediate Produced by Hydroxylamine Oxidoreductase. Proc. Natl. Acad. Sci. U.S.A. 2017, 31, 8217–8222.
- Caranto, J. D.; Vilbert, A. C.; Lancaster, K. M. Nitrosomonas europaea Cytochrome P460 Is a Direct Link between Nitrification and Nitrous Oxide Emission. Proc. Natl. Acad. Sci. USA, 2016, 113, 14704–14709.
Transition Metal Electronic Structure/X-ray Spectroscopy
- DiMucci, I.M.; Lukens, J.T.; Chatterjee, S.; Carsch, K.M.; Titus, C.J.; Lee, S.J.; Nordlund, D.; Betley, T.A.; MacMillan, S.N.; Lancaster, K.M. The Myth of d8 Copper(III), J. Am. Chem. Soc. 2019, 141, 18508-18520.
- MacLeod, K.C.; DiMucci, I.M.; Zovinka, E.P.; McWilliams, S.F.; Mercado, B.Q.; Lancaster, K.M.; Holland, P.L., Masked Radicals: Iron Complexes of Trityl, Benzophenone, and Phenylacetylene, Organometallics 2019, 38, 4224-4232.
- Carsch, K.M.; DiMucci, I.M.; Iovan, D.A.; Li, A.; Zheng, S.; Titus, C.J.; Lee, S.J.; Irwin, K.D.; Nordlund, D.; Lancaster, K.M.; Betley, T.A., Synthesis of a copper-supported triplet nitrene complex pertinent to copper-catalyzed amination, Science 2019, 365, 1138-1143.
- Lukens, J.T.; DiMucci, I.M.; Kurogi, T.; Mindiola, D.J.; Lancaster, K.M., Scrutinizing metal–ligand covalency and redox non-innocence via nitrogen K-edge X-ray absorption spectroscopy, Chem. Sci. 2019, 10, 5044–5055.
- MacMillan, S. N.; Lancaster, K. M. X-ray Spectroscopic Interrogation of Transition Metal-Mediated Homogeneous Catalysis: Primer and Case Studies. ACS Catalysis, 2017, 7, 1776–1791.
- Walroth, R. C.; Lukens, J. T.; MacMillan, S. N.; Finkelstein, K. D.; Lancaster, K. M. Spectroscopic Evidence for a 3d10 Ground State Electronic Configuration and Ligand Field Inversion in [Cu(CF3)4]1– J. Am. Chem. Soc. 2016, 138, 1922–1931.
Education
- Postdoc, Cornell University
- PhD Chemistry, California Institute of Technology
- BA Molecular Biology, Pomona College
Departments and programs
Links
Keywords
inorganic chemistry, bioinorganic chemistry, synthesis, outer-sphere coordination, small-molecule activation, climate change, nitrogen cycle
Brian Crane
George W. and Grace L. Todd Professor
Publications
- Vaidya AT, Chen CH, Dunlap JC, Loros JJ, Crane BR. Structure of a Light-Activated LOV Protein Dimer That Regulates Transcription. Sci Signal. 2011, 4
- Paul K, Gonzalez-Bonet G, Bilwes AM, Crane BR, Blair D. Architecture of the flagellar rotor. EMBO J. 2011, 30, 2962-71.
- Airola MV, Watts KJ, Bilwes AM, Crane BR. Structure of concatenated HAMP domains provides a mechanism for signal transduction. Structure 2010, 18, 436-48.
- Bhatnagar J, Borbat PP, Pollard AM, Bilwes AM, Freed JH, Crane BR. Structure of the ternary complex formed by a chemotaxis receptor signaling domain, the CheA histidine kinase, and the coupling protein CheW as determined by pulsed dipolar ESR spectroscopy. Biochemistry 2010, 49, 3824-41.
- Patel BA, Moreau M, Widom J, Chen H, Yin L, Hua Y, Crane BR. Endogenous nitric oxide regulates the recovery of the radiation-resistant bacterium Deinococcus radiodurans from exposure to UV light. Proc Natl Acad Sci U S A 2009, 106, 18183-8.
- Zoltowski BD, Vaccaro B, Crane BR. Mechanism-based tuning of a LOV domain photoreceptor. Nat Chem Biol. 2009, 5, 827-34.
- Zoltowski, B.D., Schwerdtfeger, C., Widom, J. Loros, J.J., Bilwes, A. M., Dunlap, J., C. & Crane, B.R. Conformational switching in the fungal light sensor Vivid. Science, 2007, 316 1054-1057.
- Park, S. Y., Borbat, P. P., Gonzalez-Bonet, G., Bhatnagar, J., Freed, J. H., Bilwes, A. M. & Crane, B. R. Reconstruction of the chemotaxis receptor:kinase assembly. Nat. Struct. Mol. Biol., 2006, 13, 400-407.
- Chao, X., Muff, T., Park, S., Zhang, S., Pollard, A. M., Ordal, G., Bilwes, A. M. & Crane, B.R. A receptor-modifying deamidase in complex with a signaling phosphatase reveals a mechanism of reciprocal regulation. Cell, 2006, 124, 561-571.
- Kang, S. A. & Crane, B.R. Effects of interface mutations on association modes and electron transfer rates between proteins. Proc. Natl. Acad. Sci. USA, 2005, 102, 15465-15470.
- Kers, J. A., Wach, M. J., Krasnoff, S. B., Widom, J., Cameron, K. D., Bukhalid, R. A., Gibson, D. M., Crane, B. R. & Loria, R. Nitration of a peptide phytotoxin by bacterial nitric oxide synthase. Nature, 2004, 429, 79-82.
Education
- PhD, The Scripps Research Institute
- BSc, University of Manitoba
Departments and programs
Links
Keywords
Protein electron transfer reactions, photochemistry, nitric oxide and nitration in biological systems
Peng Chen
Peter J. W. Debye Professor
Publications
See complete publication list at Group Website.
- L. Xu,† R. Ye,† M. Mavrikakis,* P. Chen* "Molecular-scale insights into cooperativity switching of xTAB adsorption on gold nanoparticles" ACS Cent. Sci. 2024, 10, 65-76.
- R. Ye,† X. Sun,† X. Mao,† F. Alfonso, S. Baral, C. Liu, G. Coates, P. Chen* "Optical sequencing of single synthetic polymers" Nature Chem. 2024, 16, 210-217.
- B. Fu,† X. Mao,† Y. Park, Z. Zhao, T. Yan, W. Jung, D. H. Francis, W. Li, B. Pian, F. Salimijazi, M. Suri, T. Hanrath, B. Barstow, P. Chen* "Single-cell multimodal imaging uncovers energy conversion pathways in biohybrids" Nature Chem. 2023, 15, 1400-1407.
- S. Baral,† C. Liu,†,* X. Mao, G. W. Coates, P. Chen* "Tuning single polymer growth via hydrogen bonding in conformational entanglements" ACS Cent. Sci. 2022, 8, 1116-1124.
- X. Mao, P. Chen* "Inter-facet junction effects on particulate photoelectrodes" Nature Mater. 2022, 21, 331-337.
- R. Ye,† M. Zhao,† X. Mao, Z. Wang, D. A. Garzón, H. Pu, Z. Zhao, P. Chen* "Nanoscale cooperative adsorption for materials control" Nature Commun. 2021, 12, 4287.
- S. Baral, C. Liu, U. K. Chakraborty, K. Kubo, X. Mao, G. W. Coates, P. Chen* "Single-chain polymerization dynamics and conformational mechanics of conjugated polymers" Chem 2021, 7, 2175-2189.
- B. Fu,† K. Sengupta,† L. A. Genova,† A. G. Santiago, W. Jung, L. Krzeminski, U. K. Chakraborty, W. Zhang, P. Chen* "Metal-induced sensor mobilization turns on affinity to activate regulator for metal detoxification in live bacteria" Proc. Natl. Acad. Sci. U.S.A. 2020, 117, 13248-13255.
- L. A. Genova,† M. F. Roberts,† Y.-C. Wong, C. E. Harper, A. G. Santiago, B. Fu, A. Srivastava, W. Jung, L. M. Wang, L. Krzeminski, X. Mao, X. Sun, C.-Y. Hui, P. Chen,* C. J. Hernandez* "Mechanical stress compromises multicomponent efflux complexes in bacteria" Proc. Natl. Acad. Sci. U.S.A. 2019, 116, 25462-25467.
- X. Mao, C. Liu, M. Hesari, N. Zou, P. Chen* "Super-resolution imaging of nonfluorescent reactions via competition" Nature Chem. 2019, 11, 687-694.
- N. Zou,† X. Zhou,† G. Chen,† N. M. Andoy, W. Jung, G. Liu, P. Chen* "Cooperative communication within and between single nanocatalysts" Nature Chem. 2018, 10, 607-614.
- C. Liu,† K. Kubo,† E. Wang,† K.-S. Han, F. Yang, G. Chen, F. A. Escobedo,* G. W. Coates,* P. Chen* "Single polymer growth dynamics" Science 2017, 358, 353-355.
- J. B. Sambur, T.-Y. Chen, E. Choudhary, G. Chen, E. J. Nissen, E. M. Thomas, N. Zou, P. Chen* "Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes" Nature 2016, 530, 77-80.
Education
- Postdoc, Harvard University, 2004-2005
- PhD, Stanford University, 2004
- BS, Nanjing University, 1997
Departments and programs
Links
Keywords
Single-molecule super-resolution imaging & manipulation, nanoscale (photo)(electro)catalysis, polymerization catalysis, bioinorganic/biophysical chemistry, bacterial cell imaging, solar and biological energy conversion