Peng Chen

Peter J. W. Debye Professor

Publications

See complete publication list at Group Website.

U. Chakraborty,^† Y. Park,^† K. Sengupta, W. Jung, C. Joshi, D. Francis, P. Chen* "A ‘through-DNA’ mechanism for co-regulation of metal uptake and efflux" Nature Commun. 2024, 15, 10555.
W. Jung,* T.-Y. Chen, A. G. Santiago, P. Chen* "Memory effects of transcription regulator-DNA interactions in bacteria" Proc. Natl. Acad. Sci. U.S.A. 2024, 121, e2407647121.
M. Zhao, W. Li, M. Yang, Z. Zhao, R. Ye, X. Mao, P. Padgett, P. Chen* "Long-range enhancement of micropollutant adsorption on metal-promoted photocatalysts" Nature Catal. 2024, 7, 912-920.
L. Xu,^† R. Ye,^† M. Mavrikakis,* P. Chen* "Molecular-scale insights into cooperativity switching of xTAB adsorption on gold nanoparticles" ACS Cent. Sci. 2024, 10, 65-76.
R. Ye,^† X. Sun,^† X. Mao,^† F. Alfonso, S. Baral, C. Liu, G. Coates, P. Chen* "Optical sequencing of single synthetic polymers" Nature Chem. 2024, 16, 210-217.
B. Fu,^† X. Mao,^† Y. Park, Z. Zhao, T. Yan, W. Jung, D. H. Francis, W. Li, B. Pian, F. Salimijazi, M. Suri, T. Hanrath, B. Barstow, P. Chen* "Single-cell multimodal imaging uncovers energy conversion pathways in biohybrids" Nature Chem. 2023, 15, 1400-1407.
S. Baral,^† C. Liu,^†,* X. Mao, G. W. Coates, P. Chen* "Tuning single polymer growth via hydrogen bonding in conformational entanglements" ACS Cent. Sci. 2022, 8, 1116-1124.
X. Mao, P. Chen* "Inter-facet junction effects on particulate photoelectrodes" Nature Mater. 2022, 21, 331-337.
R. Ye,^† M. Zhao,^† X. Mao, Z. Wang, D. A. Garzón, H. Pu, Z. Zhao, P. Chen* "Nanoscale cooperative adsorption for materials control" Nature Commun. 2021, 12, 4287.
S. Baral, C. Liu, U. K. Chakraborty, K. Kubo, X. Mao, G. W. Coates, P. Chen* "Single-chain polymerization dynamics and conformational mechanics of conjugated polymers" Chem 2021, 7, 2175-2189.
B. Fu,^† K. Sengupta,^† L. A. Genova,^† A. G. Santiago, W. Jung, L. Krzeminski, U. K. Chakraborty, W. Zhang, P. Chen* "Metal-induced sensor mobilization turns on affinity to activate regulator for metal detoxification in live bacteria" Proc. Natl. Acad. Sci. U.S.A. 2020, 117, 13248-13255.
L. A. Genova,^† M. F. Roberts,^† Y.-C. Wong, C. E. Harper, A. G. Santiago, B. Fu, A. Srivastava, W. Jung, L. M. Wang, L. Krzeminski, X. Mao, X. Sun, C.-Y. Hui, P. Chen,* C. J. Hernandez* "Mechanical stress compromises multicomponent efflux complexes in bacteria" Proc. Natl. Acad. Sci. U.S.A. 2019, 116, 25462-25467.
X. Mao, C. Liu, M. Hesari, N. Zou, P. Chen* "Super-resolution imaging of nonfluorescent reactions via competition" Nature Chem. 2019, 11, 687-694.
C. Liu,^† K. Kubo,^† E. Wang,^† K.-S. Han, F. Yang, G. Chen, F. A. Escobedo,* G. W. Coates,* P. Chen* "Single polymer growth dynamics" Science 2017, 358, 353-355.
J. B. Sambur, T.-Y. Chen, E. Choudhary, G. Chen, E. J. Nissen, E. M. Thomas, N. Zou, P. Chen* "Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes" Nature 2016, 530, 77-80.

782A ST Olin
pc252@cornell.edu
607/254-8533

Education

Postdoc, Harvard University, 2004-2005
PhD, Stanford University, 2004
BS, Nanjing University, 1997

Departments and programs

Keywords

Single-molecule super-resolution imaging & manipulation, nanoscale (photo)(electro)catalysis, polymerization catalysis, bioinorganic/biophysical chemistry, bacterial cell imaging, solar and biological energy conversion

Barbara A. Baird

Horace White Professor

Publications

[ A complete list of publications can be found on the Baird-Holowka Group webpage]

Bag, Nirmalya, D. Holowka, B. Baird. 2019. Imaging FCS Delineates Subtle Heterogeneity in Plasma Membranes of Resting Mast Cells. bioRciv
Ramezani, M., M.M. Wilkes, T. Das, D. Holowka, D. Eliezer and B. Baird. 2019. Regulation of exocytosis and mitochondrial relocalization by Alpha-synuclein in a mammalian cell model. npj Parkinson’s Disease 5(1): 1-17
Mitra, E.D., S.C. Whitehead, D. Holowka, B. Baird and J.P. Sethna. 2018. Computation of a Theoretical Membrane Phase Diagram and the Role of Phase in Lipid-Raft-Mediated Protein Organization. J. Phys. Chem. B 122(13): 3500-3513
Wakefield, D.L., D. Holowka and B. Baird. 2017. The FceRI signaling cascade and integrin trafficking converge at patterned ligand surfaces. Mol. Biol. Cell 28(23): 3383-3396
Korzeniowski, M.K., E. Wisniewski, B. Baird, D.A. Holowka and T. Balla. 2017. Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change? J. Cell Sci. 130(17): 2821-2832
Holowka, D. and B. Baird. 2017. Mechanisms of epidermal growth factor receptor signaling as characterized by patterned ligand activation and mutational analysis. Biochimica et Biophysica Acta – Biomembranes 1859: 1430-1435
Shelby, S.A., S.L. Veatch, D.A. Holowka and B.A. Baird. 2016. Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling. Mol. Biol. Cell 27(22): 3645-3658
Sun, C., D.L. Wakefield, Y. Han, D.A. Muller, D.A. Holowka, B.A. Baird and W.R. Dichtel. 2016. Graphene Oxide Nanosheets Stimulate Ruffling and Shedding of Mammalian Cell Plasma Membranes. Chem 1(2): 273-286
Wilson, J.D., S.A. Shelby, D. Holowka and B. Baird. 2016. Rab11 Regulates the Mast Cell Exocytic Response. Traffic 17(9): 1027-1041
Holowka, D. and B. Baird. 2016 Roles for lipid heterogeneity in immunoreceptor signaling Biochimica et Biophysica Acta 1861(8): 830-836
Singhai, A., D.L. Wakefield, K.L. Bryant, S.R. Hammes, D. Holowka and B. Baird. 2015. Spatially Defined EGF Receptor Activation Reveals an F-Actin-Dependent Phospho-Erk Signaling Complex. Biophys. J. 107(11): 2639-2651.
Holowka, D. and B. Baird. 2015. Nanodomains in Early and Later Phases of FcεRI Signaling. Essays in Biochemistry: Membrane Nanodomains; Vol. 57, pp. 147-163.
Kelly, C.V., D.L. Wakefield, D.A. Holowka, H.G. Craighead and B.A. Baird. 2014. Near-Field Fluorescence Cross-Correlation Spectroscopy on Planar Membrane. ACS Nano 8(7): 7392-7404.
Wilkes, M.M., J.D. Wilson, B. Baird and D. Holowka. 2014. Activation of Cdc42 is Necessary for Sustained Oscillations of Ca²⁺ and PIP2 Stimulated by Antigen in RBL Mast Cells. Biology Open 3(8): 700-710.
Chylek, L.A., D.A. Holowka, B.A. Baird and W.S. Hlavacek. 2014. An interaction library for the FcεRI signaling network. Front. Immunol. 5: 172.
Welch, M. Elizabeth, N.L. Ritzert, H. Chen, N.L. Smith, M.E. Tague, Y. Xu, B.A. Baird, H.D. Abruña and C.K. Ober. 2014. Generalized Platform for Antibody Detection using the Antibody Catalyzed Water Oxidation Pathway. J. Am. Chem. Soc. 136(5): 1879-1883.
Shelby, S.A., D. Holowka, B. Baird and S.L. Veatch. 2013. Distinct Stages of Stimulated FcεRI Receptor Clustering and Immobilization Are Identified through Superresolution Imaging. Biophys. J. 105(10): 2343-2354.
Bryant, K.L., M.A. Antonyak, R.A. Cerione, B. Baird and D. Holowka. 2013. Mutations in the Polybasic Juxtamembrane Sequence of Both Plasma Membrane- and Endoplasmic Reticulum-localized Epidermal Growth Factor Receptors Confer Ligand-independent Cell Transformation. J. Biol. Chem. 288(48): 34930-34942.
Veatch, S.L., B.B. Machta, S.A. Shelby, E.N. Chiang, D.A. Holowka and B.A. Baird. 2012. Correlation Functions Quantify Super-resolution Images and Estimate Apparent Clustering Due to Over-counting. PLoS One 7(2): e31457.
Veatch, S., E. Chiang, P. Sengupta, D. Holowka and B. Baird. 2012. Quantitative Nano-Scale Analysis of IgE-FcεRI Clustering and Coupling to Early Signaling Proteins. J. Phys. Chem. B. 116(23): 6923-6935.

660A ST Olin
bab13@cornell.edu
607/255-4095

Education

Damon Runyon Postdoctoral Fellow, National Cancer Institute, NIH
PhD, Cornell University
BS, Knox College

Departments and programs

Keywords

Biophysical studies of membrane receptor proteins, signal transduction and cellular responses

Nozomi Ando

Associate Professor

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Links

Pamela Chang

Associate Professor

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Education

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Frank C. Schroeder

Professor

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Education

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Keywords

Steven Edward Ealick

William T. and Betty R. Miller Professor, Emeritus

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Education

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Brian Crane

George W. and Grace L. Todd Professor

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Education

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Peng Chen

Peter J. W. Debye Professor

Publications

Education

Departments and programs

Links

Keywords

Richard A. Cerione

Distinguished Professor of Arts & Sciences

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Education

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Jeremy M. Baskin

Associate Professor

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Education

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Barbara A. Baird

Horace White Professor

Publications

Education

Departments and programs

Links

Keywords